Semen or sperm is a fluid that contains spermatozoa. It is secreted by the gonads (sexual glands) of male or hermaphroditic animals and humans for fertilization of female ova. Semen discharged by an animal or human is known as ejaculate, and the process of discharge is called ejaculation. Like blood, semen consists of two parts, the cellular part (spermatozoa) and noncellular part (seminal plasma). Depending on the species of animals, spermatozoa can fertilize ova externally or internally. In external fertilization, the spermatozoa fertilize the ova directly, outside of the female's sexual organs. Female fish, for example, spawn ova into their aquatic environment, which is fertilized by male the semen of the male fish. During internal fertilization, however, fertilization occurs inside the female's sexual organs. Internal fertilization takes places after insemination of a female by a male through copulation. In low vertebrates (amphibians, reptiles, birds and monotreme mammals), copulation is achieved through the physical mating of the cloaca of the male and female. In marsupial and placental mammals, copulation occurs through the vagina. Mammalian semen is a whitish, milky fluid, very viscous, containing water and small amounts of salt, protein, and fructose. The plasma portion of semen may contain dissolved water- and fat-soluble constituents, depending on the diet of the organism in question. These constituents may affect the color, odor, consistency, and taste of the semen. Contents 1 Composition of human semen 2 Semen and transmission of disease 3 Cultural views 4 See also 5 References 6 External links Composition of human semen Approximately 200- to 500-million spermatozoa (also called sperm or spermatozoans), produced in the testes, are released per ejaculation. However, they make up only about 2–5% of the volume of semen. The bulk of the semen is composed of seminal plasma, the fluid portion of semen. This fluid is contributed by the accessory male reproductive organs. Some 60% of the volume of ejaculate is produced by the seminal vesicles, and most of the remainder is generated by the prostate. A small amount of viscous mucus secreted by the bulbourethral glands contributes to the cohesive jelly-like texture of semen. Seminal plasma of humans contains a complex range of organic and inorganic constituents. They include metal and salt ions, sugars, lipids, steroid hormones, enzymes, prostaglandin hormones, amino acids and basic amines. The seminal plasma provides a nutritive and protective medium for the spermatozoa during their journey through the female reproductive tract. The normal environment of the vagina is a hostile one for sperm cells, for it is very acidic (from the native microflora producing lactic acid), viscous, and patrolled by immune cells. The components in the seminal plasma attempt to compensate for this hostile environment. Basic amines such as putrescine, spermine, spermidine and cadaverine are responsible for the smell and flavor of semen. These alkaline bases counteract the acidic environment of the vaginal canal (which is harmful to sperm), and protect DNA inside the sperm from acidic denaturation. Salts and metal ions in the semen help to create a more hospitable environment for the sperm in the vaginal canal. A typical ejaculation can contain up to 5 mg of zinc. Zinc serves to help to stabilize the DNA-containing chromatin in the sperm cells. A zinc deficiency may result in lowered fertility because of increased sperm fragility. Zinc deficiency can also adversely affect spermatogenesis. The simple sugar fructose is the main energy source of sperm cells, which rely entirely on sugars from the seminal plasma for energy. Other components of semen (mucus and texturizing proteins) serve to increase the mobility of sperm cells in the vagina and cervix by creating a less viscous channel for the sperm cells to swim though, and preventing their diffusion out of the semen. Prostaglandin hormones are involved in suppressing an immune response by the female against the foreign semen. Semen and transmission of disease The semen of a disease-free individual is harmless on the skin or if swallowed. However, semen can be the vehicle for many sexually transmitted diseases, including HIV, the virus that causes AIDS. It is also hypothesized that components of semen, such as the spermatozoa as well as the seminal plasma, can cause immunosuppression in the body when introduced to the bloodstream or lymph. Evidence for this dates back to 1898, when Elie Metchnikoff injected a guinea pig with its own and foreign guinea pig sperm, finding that an antibody was produced in response; however the antibody was inactive, pointing to a suppression response by the immune system. Further research, such as that by S. Mathur and J.M. Goust, demonstrated that non-preexisting antibodies were produced in humans in response to the sperm. These antibodies mistakenly recognized native T lymphocytes as foreign antigens, and consequently the T lymphyocytes would fall under attack by the body's B lymphocytes. Other semen components shown to spur an immunosuppressive effect are seminal plasma and seminal lymphocytes. Note that any kind of sexual or other skin contact with the semen of a person infected with HIV should be avoided, even by persons already infected with the virus, as this may cause harmful re-infection. Cultural views In some cultures, semen is attributed with special properties of masculinity. For instance, among the Etoro people of Papua New Guinea, it is believed that young boys must fellate their elders and ingest their sperm to achieve proper sexual maturation. This act may also be attributed to the culturally active homosexuality throughout these and other tribes. In some pagan circles, semen is viewed as a magical fluid which harnesses the power within the male. It is not uncommon in some communities for a pagan Priestess to copulate with two or more males at the same time to harvest their semen. It is believed that in doing so an increase in power is transferred from the males into the body of the female (Priestess). Harvesting of the ejaculate and subsequently mixing it within the body of the female is believed to greatly increase the power within the female. (Garrot-1998) Similarly, the white tantrism (or "sex magic"), espoused by "Christian" gnostic master Samael Aun Weor in over 60 books including The Perfect Matrimony, requires that a man never spill his semen in order to activate and harness his kundalini energy. See also ejaculation spermatozoon spermatogenesis pre-ejaculate capacitation sexual slang for a list of various commonly used terms for semen. Bukkake -- Japanese Semen fetish pornography. Kim Kelly -- dieting with semen. cum shot References Mann T, Lutwak-Mann C. 1981. Male Reproductive Function and Semen. Berlin: Springer-Verlag. ISBN 3-540-10383, 0-387-10383. Shivaji S, Scheit K-H, Bhargava PM. 1990. Proteins of seminal plasma. New York: John Wiley & Sons. ISBN 0-471-84685-6. External links Lipid composition of human semen "What is semen made of?" by Fred Guerra at JackinWorld.com "Semen Production and ejaculation" by M.J. Ecker at JackinWorld.com "factors that affect spermatogenesis" Can semen cure the blues? Hormones in semen may help to ease female depressionaf:Semen Search Term: "Semen" Categories: Andrology | Reproductive system